Comparative effectiveness of the complex drugs based on imidacloprid and moxidectin against ecto- and endoparasitic infestations of cats

Treatments of ecto- and endoparasitic infestations cats adopt drugs based on imidacloprid moxidectin. Therefore, the objective our study was comparing spot-on applied complex drugs, which have different action mechanisms their active agents, during cats. We provide data effectiveness antiparasitic drug Megastop Ultra for Cats, in comparison to Advocate Cats drug, used treatment prophylaxis breeds, ages, sexes body weights. Entomological examination experimental control groups revealed fleas such as Ctenocephalides felis Pulex irritans, with infestation intensity 50 90 specimens per individual, average measuring 65.3 ± 3.37 ectoparasitic insects animal. Clinically, it manifests unrest animals itching. The efficacy tested against siphonapterosis 95.4% 8th h after application, whereas 97.9%. Starting from first third days usage no were found According results acarological examination, suffered Otodectes cynotis mites, equaling 4 10 animal, being 7.4 0.5 mites Otoacariasis accompanied by itching, reddening auricle, sites moderately thick scabs crusts. On 7th day treating otoacariasis cats, produced 82.6% 84.5% efficacy. 14th treatment, we O. internal surface auricle external acoustic meatus. conducted parasitological examinations groups, diagnozed spontaneous endoparasites, nematode pathogens digestive tract – Toxocara cati Ancylostoma tubaeforme. (ІІ) T. invasion accounted 60 120 eggs one gram feces (ЕGF), 90.4 4.2 ЕGF, while A. tubaeforme 20 56 39.1 2.3 respectively. nematodoses cats’ manifested loss appetite, frustration, paleness mucous membranes, some vomittd had mild diarrhea. After worm removal, carried out coprological helminths so identify indexes parasitic efficiacy drugs. determined that toxocariasis removal 95.1%, 98.0%. both 100%. helminthological 7 14 ancylostomiasis utilized doses recommended manufacturers, exerted 100% effectiveness. Moreover, field trials single applications manufacturers good response among negative impact them, regardless breed, age, sex weight.